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| DHAP (chemotherapy) ： ウィキペディア英語版 |
DHAP (chemotherapy)
DHAP in context of chemotherapy is an acronym for chemotherapy regimen that is used for remission induction in cases of relapsed or refractory Non-Hodgkin lymphoma and Hodgkin disease.〔(Effective salvage therapy for lymphoma with cisplatin in combination with high-dose Ara-C and dexamethasone (DHAP) )〕 It is usually given for 2-3 courses, then followed by high-dose chemotherapy and autologous stem cell transplant. In combination with anti-CD20 monoclonal antibody Rituximab (Rituxan, Mabthera) it is called R-DHAP or DHAP-R.
()-DHAP regimen consists of:
# Rituximab, a monoclonal antibody, directed at B-cell surface antigen CD20
# (D)examethasone, a glucocorticoid hormone
# (H)igh-dose (A)ra-C - cytarabine, an antimetabolite;
# (P)latinol (cisplatin), a platinum-based antineoplastic agent with an alkylating mechanism;
== Dosing regimen ==
== References ==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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